http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-102012002468-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7c17dba509c1efd3a166bf9f7b3dd24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_486383bcdc108830b08d6478134bae03 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-02 |
| filingDate | 2012-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7eca49e3b64a9cf0276bc65a6a335a84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_421871edfee74f479dbf37877b8790a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48d4a4d62b4a76adf0c7536ddd9cc4f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5ec1073555d95a1e1f8407beb72368a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4769072a8c65abb9165c424fa9d67341 |
| publicationDate | 2015-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-102012002468-A2 |
| titleOfInvention | Recombinant multiepitope protein, its procurement process and its applications related to hepatitis b |
| abstract | Recombinant multiepitope protein, its procurement process and its applications related to hepatitis b. This invention relates to a specially engineered recombinant antigenic protein containing different epitopes or most prevalent viral regions of the most representative hepatitis b virus in Brazil and worldwide. It is a multiepitope protein containing appropriately sized flexible connectors to facilitate the connection between different epitopes or viral fragments. This structural feature gives the protein greater sensitivity and specificity in recognizing anti-hbc antibodies. In addition, multiepitope protein induces a broader immune response that is desirable to address different applications related to hepatitis b detection, immunization, prevention and treatment, making it useful in the preparation of different products of interest to the pharmaceutical and biotechnology industries. such as in vitro diagnostic kits for the detection of hepatitis b from physiological samples of humans, and immunogenic compositions, vaccines, drugs or biopharmaceuticals to prevent and treat this disease. Additionally, as an input for the production of monoclonal antibodies. Another aspect of the present invention is related to the process of obtaining such protein, based on cloning and heterologous expression in microorganisms. |
| priorityDate | 2012-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.