| abstract |
"2-PYRIDONE DERIVATIVES AS NEUTROPHYLE ELASTASE INHIBITORS". The present invention provides novel compounds of formula (I): wherein R¬1¬, R¬4¬, R¬5¬, G¬1¬, G¬2¬, X, L, Y¬1¬, Y¬ 2¬, en are as defined in the specification and also the optical isomers, racemates and tautomers thereof, as well as the pharmaceutically acceptable salts thereof. The invention also provides processes for preparation, compositions containing said compounds and their use in therapy procedures. The compounds of the invention are neutrophil elastase inhibitors. |