abstract |
"Biphenylcarboxamides Replaced by N-Aryl Piperidine as Inhibitors of APOLIPOPROTEIN B Secretion". The present invention relates to N-aryl piperidine substituted biphenylcarboxamide compounds of formula (I), methods for preparing such compounds, pharmaceutical compositions comprising such compounds, and the use of such compounds as a medicament for the treatment of hyperlipidemia, obesity and type II diabetes. The compounds act as apolipoprotein B inhibitors. |