abstract |
"COMPOUND OR A PHARMACEUTICALLY ACCEPTABLE SALT OF THIS PHARMACEUTICALLY ACCEPTABLE, AND USE OF THE COMPOUND OR A PHARMACEUTICALLY ACCEPTABLE SALT OF THIS PHARMACEUTICALLY". A compound of Formula (I), wherein A together with the carbon atoms to which it is attached forms a fused 5-membered heteroaryl ring, wherein said heteroaryl ring contains 1 or 2 heteroatoms selected from O, N and S and wherein the 5-membered ring containing G is attached to the ring formed by A at the meta position with respect to the #-labeled carbon bridgehead in Formula (I). G is selected from O, S and NR ^ 5 ^; Z is selected from N and CR ^ 6 ^; Q ^ 1 ^ is selected from optionally substituted aryl and heteroaryl, and the substituents of R ^ 1 ^ to R ^ 6 ^ are as defined in the text for use in producing an anti-angiogenic effect in a warm-blooded animal such as the human being. |