abstract |
"METHODS OF USING ARTEMISININ TYPE COMPOUNDS TO PREVENT OR DELAY THE APPEARANCE OF CANCER". The invention provides methods for preventing or delaying the onset of cancer by administering free radical generating agents to an individual. Representative free radical generating agents include endoperoxide compounds, such as sesquiterpene compounds harboring endoperoxides such as artemisinin and its analogs, arteflen and its analogues, 1,2,4-trioxanes and 1,2,4,5-tetraoxanes. Intracellular iron concentrations may be increased in their levels by administration of iron salts or complexes. |