abstract |
"BENZOILGUANIDINES DERIVED FROM FLUORATED CYCLALKYLES AND THEIR EMPLOYMENT AS A MEDICINAL PRODUCT". The present invention relates to fluorinated cycloalkyl-derived benzoylguanidines of formula (I) which are suitable as anti-arrhythmic drugs with cardioprotective component for prophylaxis against infarction and treatment for infarction as well as treatment of angina pectoris. They also preventively inhibit pathophysiological steps in the onset of induced ischemic damage, particularly in the onset of ischemic-induced cardiac arrhythmias and heart failure. |