| abstract |
"METHOD OF TREATMENT OF DISORDERS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND USE OF A COMPOUND". The present invention relates to a group of IH-1,2,4-triazole-3-carboxamide derivatives, methods for the preparation of such compounds, and pharmaceutical compositions containing at least one of these compounds as an active ingredient. These 1H-1,2,4-triazole-3-carboxamide derivatives are potent CB-1-cannabinoid receptor agonists, partial agonists, inverse agonists or antagonists useful for the treatment of disorders involving cannabinoid neurotransmission. The compounds have the general formula (I): wherein R and R 1 -R-3 have the meanings given in the descriptive report. |