abstract |
"LIQUID NICOTINE BUFFERED COMPOSITION FOR PULMONARY ADMINISTRATION". The composition consists of a liquid pharmaceutical preparation comprising nicotine in any form for administration essentially to the lungs. The preparation is acidified and / or alkalized by buffering and pH regulation, which provides a t max of nicotine in a patient's arterial blood within a short time after administration. Administration preferably comprises spraying an aerosol into the oral cavity for subsequent delivery essentially to the lungs. A process for the manufacture of the preparation is also included, as well as the use of the preparation in therapy, such as for the treatment of smoking addiction. |