| abstract |
"C-17 SPYROLACTONIZATION AND 6.7 STEROID Oxidation". New processes are provided for C-17 spirolactonization and 6.7 oxidation of steroid compounds. In certain preferred embodiments, the present invention provides for the preparation of steroid compounds which are useful in the preparation of 9,11? -Epoxy-17? -Hydroxy-3-oxopregn-4-ene?? methyl, 21-dicarboxylate, -lactone (otherwise referred to as eplerenone or epoxymexrenone). |