http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-0307504-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40a92325286ca98dbffa06d2c67ed064 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 2003-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da31a03348cc9d2e6969e2f4bc8c698f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93665e3fc9cc00f9d7bc090b3eae1931 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b74c47cf3711470f4cda723a8bcbc06d |
| publicationDate | 2004-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-0307504-A |
| titleOfInvention | Pharmaceutically acceptable compound or salt, pharmaceutical composition, methods for treating disease, for enhancing a therapeutic effect of a snc agent, for enhancing short-term memory in a patient, for determining the presence or absence of gabaa receptors in a sample, and to alter gabaa receptor signal transducer activity, packaging, and use of a compound or salt |
| abstract | "PHARMACEUTICALLY ACCEPTED COMPOUND OR SALT, PHARMACEUTICAL COMPOSITION, METHODS TO TREAT DISEASES, TO POTENTIAL A CNS AGENT THERAPEUTIC MEMORY, TO IMPROVE SHORT TERM MEMORY IN A PATIENT, OR TO DETERMINE A GENDER A SAMPLE, AND TO ALTER THE GABA ~ A ~ RECEIVER SIGNAL TRANSDUCTIVE ACTIVITY, PACKAGING, AND USE OF A COMPOUND OR SALT ". Heterocyclic compounds such as 3,4,5,6-tetrahydro 2,3,10-triaza-benzo [e] azulene-1-carboxylic arylamides, 5,7-dihydro-6H-pyrazolo [3,4-h] acid quinoline-9-carboxylic arylamides, 5,7-dihydro-6H-pyrazolo [3,4-h] quinazoline-9-carboxylic acid arylamides, 2,4,5,6-tetrahydro1,2,6,7-tetraazaic acid as-indacene-8-carboxylic arylamides and related compounds are disclosed. These compounds are highly selective GABA-A ~ brain receptor agonists, antagonists or inverse agonists or GABA-A ~ brain receptor agonists, antagonists or inverse agonists prodrugs and are therefore useful in the treatment of anxiety, depression, disorders. from sleep and stroke, benzodiazepine drug overdose, Alzheimer's dementia, and memory impairment. Pharmaceutical compositions including packaged pharmaceutical compositions are also provided. Further useful intermediates for the synthesis of pyrazolecarboxylic acid acrylamides are provided. The compounds of the invention are also useful as probes for localizing GABA-Aβ receptors in tissue samples. |
| priorityDate | 2002-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.