abstract |
"1,2,4-Triazole Derivatives Containing a Sulfamate Group as Aromatase Inhibitors". A compound of Formula (I) is provided, wherein each T is independently selected from H, hydrocarbyl, -FR, and a bond with one of D, E, P or Q, or forms a ring together with one of P and Q; Z is a suitable atom whose valence is m; D, E and F are independently among them an optional bonding group, wherein when Z is a nitrogen, E is a group except for CH ~ 2 ~ and C = O; P, Q and R are independently among themselves a ring system; and at least Q comprises a sulfamate group. |