http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-0209446-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0065 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N- |
| filingDate | 2002-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76ba8a40b86b873b62f7534db8fba7b0 |
| publicationDate | 2004-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-0209446-A |
| titleOfInvention | Method to identify myeloperoxidase inhibitors, and use of a method |
| abstract | "METHOD FOR IDENTIFYING MYELOPEROXIDASE INHIBITORS, AND USING A METHOD". A test method for detecting myeloperoxidase enzyme inhibitors, said method comprising the steps of: reacting myeloperoxidase with hydrogen peroxide and a chloride source to generate hypochlorous acid in the presence of a potential inhibitor of said myeloperoxidase; reacting any hypochlorous acid formed with a suitable amine to form the corresponding chloramine; optionally removing any unreacted hydrogen peroxide; reacting any chloramine with an appropriate detector molecule in the presence of iodide to form oxidized detector molecule; determining the amount of oxidized detector molecule formed by measuring absorbance or fluorescence at a suitable wavelength; identify as myeloperoxidase inhibitors those compounds that cause the decrease in the amount of oxidized detector molecule formed. And the use in diagnostic tests for myeloperoxidase activity is described. |
| priorityDate | 2001-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.