| abstract |
"USE OF GAL3 RECEPTOR ANTAGONISTS FOR TREATMENT OF DEPRESSION AND / OR ANXIETY AND COMPOUNDS USED IN SUCH METHODS". This invention relates to pyrimidine and indolone derivatives which are selective GAL3 receptor antagonists. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and / or anxiety comprising administering to the subject an amount of a compound of the invention effective to treat depression and / or anxiety of the subject. The invention also provides a method of treating depression and / or anxiety in a subject comprising administering to the subject a composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a GAL3 receptor antagonist. |