http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-0206650-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f6e33603375c486b0ab3505830af9e8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2002-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c72407fce616fbe3148bc3c07d5a9427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9eacfbd081e0faca1103d71621f86543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3690c539008df0933afa0409b64ee0ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf2a2148b6ccdba0977e0b86a7034afd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9f708d24ad2321e4da78b0cbbb3810a |
| publicationDate | 2004-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-0206650-A |
| titleOfInvention | Compound, pharmaceutical composition, use of at least one compound, and process for preparing a compound |
| abstract | "COMPOUND, PHARMACEUTICAL COMPOSITION, USE OF AT LEAST ONE COMPOUND, AND PROCESS FOR PREPARING A COMPOUND". Compounds of formula (I): wherein: A is a pyrrol ring; R4 is an optionally substituted aryl or heteroaryl group; R 2 is a optionally substituted nitrogen-containing heteroaryl group; and R3 is formulas (IIa), (IIb) or (IIc), wherein m is 1 or 2, one of D and E is nitrogen and the other> C (R5-5) - (where R ^ 5 ^ is hydrogen, a <244> substituent or a <225> substituent, B is a 4-7 membered nitrogen-containing heterocyclic ring, and R ^ 4 ^ is 1 to 3 substituents of the <244> substituent group , Substituent group <225> and substituent group <sym>, provided that R1 and R3 are attached to the two atoms of said pyrrole ring which are adjacent to the atom of the pyrrole ring to which said substituent R2 is. substituent group <244> consists of hydroxyl, nitro, cyano, halogen, alkoxy, halogen alkoxy, alkylthio and halogen alkylthio groups and groups of the formula -NR4a ^ R4B4 (where R4a4 and R4) (are hydrogen, alkyl, alkenyl, alkynyl, aralkyl and alkylsulfonyl, or R4a and R4b4 together with the nitrogen atom to which they are attached form a heterocyclyl); of alkyl, alkenyl groups and optionally substituted alkynyl, and aralkyl and cycloalkyl groups; <sym> substituent group consisting of oxo, hydroxyimino, alkoxyimino, alkylene, alkylenedioxy, alkylsulfinyl, alkylsulfonyl, optionally substituted aryl, optionally substituted aryloxy, alkylidenyl and aralkylidenyl groups exhibit excellent activity against the production of inflammatory cytokines. |
| priorityDate | 2001-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.