http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-0202783-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8be6a6c990669567cc455d32b00535e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K2-00 |
| filingDate | 2002-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbbb7fa6e1b3b43c3a412a70bc329283 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d79c84a7dc98cff2ab6a1ec43dee0d5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b55fd40e9b50fa626926a3097bc26bfb |
| publicationDate | 2003-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-0202783-A |
| titleOfInvention | Process for rapid synthesis of a peptide in solution in an organic solvent or a mixture of organic solvents, methods for combinatorial synthesis of peptide collection and for automated peptide synthesis in solution, and peptide or a mixture of peptides |
| abstract | "PROCESS FOR THE FAST SYNTHESIS OF A PEPTIDE IN SOLUTION IN AN ORGANIC SOLVENT OR IN A MIX OF ORGAN SOLVENTS PEPTIDES ". The present invention relates to a process for the rapid synthesis of a peptide in solution, the process comprising the repetitive cycles of steps (a) - (d): (a) a coupling step using an excess activated carboxylic component to acylate an amino component, (b) a blast chilling step in which a remover is used to remove residual activated carboxylic functions, in which the remover may also be used for deprotection of the growing peptide, (c) one or more aqueous extractions and optionally (d) a separate deprotection step following one or more aqueous extraction steps, characterized in that the process comprises at least one step (b), referred to as step (b '), in which an amine comprising a free anion or a latent anion is used as a remover of residual activated carboxylic functions. During the process of this invention the growing peptide need not be isolated until the final peptide sequence has been obtained. This highly efficient process is useful for the production of high purity oligo- and polypeptides. |
| priorityDate | 2001-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.