abstract |
"PROCESS FOR PREPARING (3-CYANO-1H-INDOL-7-IL) (4- (4-FLUOROPHENETILE) PIPERAZIN-1-IL) -METHANONE AND SALTS THEREOF". The invention relates to a process for the preparation of (3-cyano-1H-indol-7-yl) [4- (4-fluorophenethyl) piperazin-1-yl] methanone and its salts, characterized in that wherein an indole ester of formula II wherein R is as defined in Claim 1 is converted to 3-cyano-1H-indol-7-carboxylic acid by steps (1) to (4) according to Claim 1. and this is reacted with 1- [2- (4-fluorophenyl) ethyl] piperazine or salts thereof to produce the product. |