| abstract |
"PHARMACEUTICAL COMBINATION OF ANGIOTENSIN II ANTAGONISTS AND ANGIOTENSIN I CONVERTER ENZYME INHIBITORS". The invention relates to a method of treating indications which may be positively influenced by inhibition of AT ~ 1-mediated effects, preservation of Angiotensin II AT-2 receptor-mediated effects and ACE inhibition. thus also increasing bradykinin-mediated effects, for example to reduce the incidence of stroke, acute myocardial infarction or cardiovascular death, or of indications associated with increased receptors for AT ~ 1 ~ in the subepithelial area or increased receptors for AT ~ 2 - in the epithelia, comprising the combined administration of an effective amount of an Angiotensin II antagonist and an ACE inhibitor, pharmaceutical compositions containing an Angiotensin II antagonist together with an ACE inhibitor and the use of an Angiotensin antagonist. II and an ACE inhibitor for the production of corresponding pharmaceutical compositions. |