| abstract |
"ALPHA-SUBSTITUTED STEROID COMPOUND, USE OF THE SAME, TREATMENT METHODS FOR SELECTIVE ACTIVATION OF ALPHA SUBTITUS RECEPTORS, AND FOR HORMONAL REPLACEMENT OR CONTRACEPTION THERAPY, AND," FARM COMPOSITION. The invention provides a substituted 16β steroid compound having formula 1 wherein the dotted ring is a fully saturated, fully aromatic ring or a saturated double bond <30> 5-10 ring; R2 is (C1 -C1 -C3) alkyl or (C1 -C2 -C3) alkenyl, and each of these groups may be substituted with one or more halogens; R 2 is C (C 1 -C 4) alkyl, (C 2 -C 4) alkenyl, or methylene, and each of these groups may be substituted with one or more halogens; R3 is methyl or ethyl; or a prodrug thereof, which can be used for selective estrogen receptor treatment. |