| abstract |
"NUCLEOSIDES OF FIRY [2,3D] PYRIMIDINE AND PIRIMIDINE [4,5-D] PYRIMIDINE". A purine nucleoside analog includes a pyrido [2,3-d] pyrimidine or a pyrimido [4,5-d] pyrimidine and additionally has a sugar moiety that is optionally modified at the C2 <39>, C3 <39> position. , C4 <39> and / or C5 <39>. Particularly contemplated compounds also include prodrug forms of the purine nucleoside analogs, and both the purine nucleoside analogs and the corresponding prodrugs are employed in reducing neoplastic cell development. |