| abstract |
"DEVICE FOR CONTROLLED RELEASE DURING A EXTENDED TIME PERIOD OF A DRUG WITH ANTIPROGESTINIC PROPERTIES". The present invention relates to a device for the controlled release over a prolonged period of time of a drug with antiprogestin properties, said device comprising a core comprising said drug, - optionally a membrane surrounding said core, wherein said core and / or membrane is made of a siloxane-based elastomer composition comprising at least one elastomer and possibly a non-crosslinked polymer. The device is characterized by the fact that the elastomer composition comprises poly (alkylene) oxide groups and in which the poly (alkylene) oxide groups are present in the elastomer or polymer as alkoxy-terminated grafts of polysiloxane units, or as blocks, said grafts or blocks being connected to the polysiloxane units by silicon-carbon bonds, or as a mixture of these forms. |