http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-0015401-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-08 |
| filingDate | 2000-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79faaa36863f46d3354f6064184246f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c1f74a97edf105e352f40668a6dc403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72002b8cb0bee0750a0cd99f4f52cda3 |
| publicationDate | 2002-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-0015401-A |
| titleOfInvention | [(indol-3-yl) -cycloalkyl] -3-substituted azetidines for the treatment of central nervous system disorders |
| abstract | Invention Patent: "[(INDOL-3-IL) -CYCLOLOQUIL] -3-SUBSTITUTED AZETIDINES FOR THE TREATMENT OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM". This invention relates to the new compounds, pharmaceutical compositions and processes of use of the compounds in the treatment of disorders of the central nervous system, such as anxiety and depression, the compounds having the formula (I), in which: X is NR, O , S (O) ~ m ~ is 0 to 2; n is 0 to 4; Ar is an aryl group of 6 to 12 carbon atoms, optionally substituted with 1 to 3 R ~ 3 ~ groups or a hetoroaryl group of 4 to 10 carbon atoms, optionally substituted with 1 to 3 R ~ 3 ~ groups; R and R ~ 2 ~ are independently H, straight chain alkyl of 1 to 6 carbon atoms, branched alkyl of 3 to 6 carbon atoms, cycloalkyl of 3 to 6 carbon atoms, alkoxycarbonyl of 1 to 6 carbon atoms, alkylcarbonyl of 1 to 6 carbon atoms, aminocarbonyl or alkylaminocarbonyl of 1 to 4 carbon atoms; R ~ 1 ~ and R ~ 3 ~ are independently H, straight chain alkyl of 1 to 4 carbon atoms, branched alkyl of 3 to 6 carbon atoms, cycloalkyl of 3 to 8 carbon atoms, halo, alkoxy group of 1 to 4 carbon atoms, haloalkyl of 1 to 4 carbon atoms, OH, nitro, amino, sulfonyl, CN, carboxy, alkoxycarbonyl of 1 to 4 carbon atoms, alkylcarbonyl of 1 to 4 carbon atoms, aminocarbonyl or 1-alkylaminocarbonyl to 4 carbon atoms; and all crystalline forms or a pharmaceutically acceptable salt thereof. |
| priorityDate | 1999-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.