| abstract |
"HCV PROTEINS WITH REVERSIBLE OXYREDUCTION AND CONFORMATION SIMILAR TO NATIVE". The present invention relates to HCV proteins in which the cysteine residues are reversibly protected during purification. Eventually, this purification procedure results in HCV proteins with biological activity and a conformation similar to the native one, which have corresponding epitopes. The present invention also relates to methods of drug screening, using these HCV proteins, and diagnostic and therapeutic applications, such as vaccines and medications. |