| abstract |
"BENZODIAZEPINE DERIVATIVES". The present invention relates to compounds of the general formula (I) in which X is a single bond or an ethinedyl group, in which, in the case of X being a single bond, R ^ 1 ^ is halogen or phenyl which is optionally substituted with halogen, lower alkyl, halo lower alkyl, lower alkoxy, halo lower alkoxy, or cyano; in the case of X being an ethinedyl group, R1 is phenyl, optionally substituted with halogen, lower alkyl, lower alkyl halo, lower cycloalkyl, lower alkoxy or lower alkoxy halo; R ^ 3 ^ is a 5- or 6-membered aryl or heteroaryl that is optionally substituted. The compounds according to the invention can be used to treat or prevent acute and / or chronic neurological disorders including psychosis, schizophrenia, Alzheimer's disease, cognitive disorders and memory deficits. |