http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-0014115-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0efa077d881a96aeb1e29b21ef1bbb58 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-125 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
| filingDate | 2000-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da3a3ebd367a336f8307a68efba83fb9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_476cdfe6cdfabec61c83a98bbf25055c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9de0c54181842e296a98a0a9efe27d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e67da236e44a71f411e990f24ae095c8 |
| publicationDate | 2002-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-0014115-A |
| titleOfInvention | Methods of producing a panto-compound, pantothenate and beta-alanine, of increasing the production of a panto-compound and of edentifying compounds that modulate the activity of pantothenate kinase, recombinant microorganism, vector, isolated nullic acid molecule, polypeptide and protein pantothenate kinase isolated |
| abstract | "METHODS OF PRODUCING A PANTO-COMPOUND, PANTHOTENATE AND BETA-ALANINE, OF INCREASING THE PRODUCTION OF A PANTO-COMPOUND AND OF IDENTIFYING COMPOUNDS THAT MODULATE THE ACTIVITY OF THE KINASE PANTOTENATE, RECOMBINANT MICROORGANISM, VECTOR, NUCLEY, MOLECULE OF PANTOTENATE KINASE ISOLATED ". The present invention depicts methods of producing panto-compounds (e.g., pantothenate) using microorganisms in which the biosynthetic pathway of pantothenate and / or the biosynthetic pathway of isoleucine-valine and / or the biosynthetic pathway of coenzyme A has been manipulated. Methods that depict microorganisms that overexpress ketoopantoate reductase as well as microorganisms that overexpress aspartate <244> -discarboxylase are provided. Methods of producing panto-compounds in a precursor-independent manner and in high yield are described. Recombinant microorganisms, vectors, isolated nucleic acid molecules, genes and gene products useful in the practice of the above methodologies are also provided. The present invention also depicts a previously unidentified microbial pantothenate kinase gene, coaX, as well as methods of producing panto-compounds that use microorganisms having modified pantothenate kinase activity. Recombinant microorganisms, vectors, isolated coaX nucleic acid molecules and purified CoaX proteins are depicted. Also described are methods for identifying the pantothenate kinase modulators that use the recombinant microorganisms and / or the purified CoaX proteins of the present invention. |
| priorityDate | 1999-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 286.