| abstract |
Patent of Invention: "PHARMACEUTICAL COMPOSITIONS FOR ORAL AND TOPIC ADMINISTRATION". A method for increasing the viscosity of a pharmaceutical formulation for oral or topical administration comprises the steps of combining a) an effective amount of one or more hydrophobic active ingredients; (b) 5 to 50% of one or more compounds selected from fatty acid polyglycerol esters of 6-15 glycerol units; (c) 5 to 50% of one or more compounds selected from polyglycerol esters of fatty acids and / or unsaturated fatty acids with 2-12 glycerol units; (d) 5 to 50% of one or more compounds selected from macrogol glycerol triglycerides, partial glycerides or fatty acid esters or macrogol fatty acid esters and concurrently the ratio of components b) and c) is 0.1: 1 to 10 : 1, and wherein upon dilution with water 1: 1 by volume, the viscosity of the formulation increases by at least 5 times compared to the undiluted composition. |