| titleOfInvention |
nucleic acid, nucleotide probe or primer, nucleotide primer, processes for amplifying a nucleic acid, for detecting the presence of a polypeptide or a nucleic acid and for selecting an active compound on cholesterol metabolism, diagnostic kits for detecting the presence of a polypeptide and nucleic acid and for amplification of a nucleic acid, recombinant vector, recombinant host cell, polypeptide, antibody, pharmaceutical composition and use of a nucleic acid, recombinant vector and polypeptide |
| abstract |
"NUCLEIC ACID, NUCLEOTHYTIC PROBE OR INITIATOR, NUCLEOTHYTIC INITIATOR, PROCESSES FOR AMPLIFICATION OF A NUCLEIC ACID, TO DETECT THE PRESENCE OF A NUCLEIC ACID AND TO SELECT A NUCLEIC ACID FOR THE USE OF AN ATTENTION OF A COMBINATION OF AN AGRICULTURAL LABEL. PRESENCE OF A POLYPEPTIDE AND A NUCLEIC ACID AND FOR AMPLIFICATION OF A NUCLEIC ACID, RECOMBINANT VECTOR, RECOMBINANT HOSTING CELL, POLYPEPTIDE, ANTIBODY COMPOSITION AND A UTILIZATION OF PHARMACEUTICAL, UTILIZATION AND A UTILIZATION. The invention relates to nucleic acids corresponding to different exons and introns of the ABC1 gene which is shown to be a gene causing pathologies linked to dysfunction of cholesterol metabolism causing diseases, such as atherosclerosis, more particularly disturbance of reverse cholesterol transport, and, more particularly, FHDs, such as Tangier disease. |