Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 |
filingDate |
2000-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c12ae6544419db32891b2317536f29d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c10f4df9ee7316ed5639cab075f5eb4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4a7820f446dc563ce02bc472043a1e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3c6af30cbd5eb6d8c1b0884dcc87738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2955aef7be740d8b2f94ff0b43c84519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0dc8387fe55027179cba979908906f27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e171d7a26391cf5be439ec9639c91979 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3ef4014b694767f7673c5a2df32fbfc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c68f8aaa2b90a61d3bb90e72d327ee8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46a30cfd915cb1684da8fda300d6227c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efdfc7e7bb9f74e4c2cf7801fa9764a5 |
publicationDate |
2002-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
BR-0010485-A |
titleOfInvention |
Formulations of erythromycin derivatives of prolonged release |
abstract |
"FORMULATIONS OF PROLONGED RELEASE ERYTHROMYCIN DERIVATIVES". a pharmaceutical composition is disclosed for prolonged release of an erythromycin derivative into the gastrointestinal environment. The composition comprises an erythromycin derivative and a pharmaceutically acceptable polymer, such that when ingested orally, the composition induces a statistically significantly lower C ~ max in plasma than an immediate release composition of an erythromycin derivative while maintaining substantially bioavailability equivalent to that of the immediate release composition of erythromycin derivative under multiple dosing. The compositions of the invention have an improved taste profile and reduced gastrointestinal side effects as compared to those for the immediate release composition. |
priorityDate |
1999-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |