http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BR-0006246-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1344c5c0f7a3b561aa76dfefb893f85f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0034 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J5-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B29C41-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F13-20 |
| filingDate | 2000-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46319a489b8ffd2e1db626282b28684a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e0acab692f3b18f60c1b1232d77c86b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_880e080020a0f3ef9d3fd3b5995e6beb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65e62f92d5dc656819624a4ac754444a |
| publicationDate | 2002-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BR-0006246-A |
| titleOfInvention | Method of preparing a water-soluble film |
| abstract | "METHOD OF PREPARING A WATER SOLUBLE FILM". The present invention provides a method of preparing a water-soluble film. The method comprises (a) preparing a solution comprising a film former, a water soluble plasticizer, a pharmaceutically active agent, and a solvent; (b) drying the solution at a temperature of about 50 to about 100 ° C, to form a film; and (c) curing the film at a temperature of about 15 to about 60 <198> C and at a relative humidity of at least about 30%. The film former is a polyacrylic acid, cellulose derivatives, a polyethylene oxide, a polyvinyl alcohol, or any combination of any of the foregoing. The water-soluble plasticizer contains at least one of a hydroxyl, starch, or amino group, and has a boiling point greater than about 150 <198> C. The water-soluble film of the present invention can be incorporated into vaginal devices, such as tampons and applicators. This method produces a uniform and homogeneous film, which is more flexible and soaks less than previous water-soluble films, especially those incorporated in vaginal dosage forms. As a result, the film is less irritating. In addition, unlike most water-soluble films of the prior art, the film can be shaped to provide a larger contact area within a body cavity, such as the vagina, in order to increase drug release. The film is also non-cluttered. |
| priorityDate | 1999-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458397310 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID962 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419512635 |
Total number of triples: 26.