http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BG-99679-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e493dbb326bdb84242fbc9af833f128e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D281-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-554 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D281-10 |
| filingDate | 1995-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44d00d989a05b9c878090cdb777d3108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b17242fec8a0964cfd277a0ae84f17fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bf7ebb0e6f918490b1bdd79336eabeb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b16241b7228ab1f5cd842617bb0ad83 |
| publicationDate | 1996-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BG-99679-A |
| titleOfInvention | 2,3,4,5-TETRAHydro-1,4-benzothiazepines, METHODS FOR THE PREPARATION AND USE OF THEME THERAPEUTIC |
| abstract | The compounds are used to treat seizures and / or neurological disorders such as epilepsy and / or as neuroprotective agents to prevent conditions such as stroke. They have a form in which n is 0 or 1, R1, R2, R6 and R7 independently represent hydrogen, R3 and R4 independently of one another denote hydrogen or methyl, or together form an imino, methylimino, phenylimino, hydroxyimino or methoxyimin; R 5 is hydrogen or methyl, or when R 3 and R 4, independently of one another, are hydrogen or methyl, R 5 is hydrogen, methyl, formyl, acetyl, propionyl, benzoyl, methylsulfinyl, methylsulfonyllyls ethylsulfonyl, R 8 is hydrogen, methyl, fluoro or chloro and R9, R10 and R11 are each independently hydrogen, provided that: R1 - R11 do not simultaneously represent H; when n is 0 and R1 - R4 and R6 - R11, independently of one another, denote H, then R5 is other than benzoyl or acetyl, and when n has a value of 0 or 1 and R1 - R3 and R5 - R11, independently of one on the other, denote H, R4 is other than methyl. The invention also relates to stereoisomers and pharmaceutically acceptable salts of the compounds and to a process for their preparation. |
| priorityDate | 1992-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 168.