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filingDate 2002-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d9be710b3820da64cd3472573d2d6ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17bfe5c303e827d54ff18ac716e0753d
publicationDate 2009-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber BG-65734-B1
titleOfInvention LIQUID MUCCO ADHESIVE PHARMACEUTICAL COMPOSITION
abstract The invention relates to a liquid mucoadhesive pharmaceutical composition for mucosal treatment and can be used in medical practice in the form of oral, ocular, rectal, vaginal, nasal and periodontal medications. The liquid mucoadhesive composition contains, by weight, %: biologically active substance from 0.01 to 10.00, mucoadhesive substance from 0.01 to 10.00, preservative from 0.01 to 5.00, NaCl from 0.10 to 0.90, and phosphate buffer at pH 5-7 to 100, and the relative viscosity is 5.00-500.00 and the relative adhesive capacity is from 105.0 to 120.0%. The resulting mucoadhesive composition provides easy diffusion, good absorption and improved bioavailability. The composition has a prolonged stay on the mucosa and allows to obtain the required therapeutic effect at lower doses. In addition, the composition has very good fluidity and mucoadhesiveness.
priorityDate 2002-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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