abstract |
The pharmaceutical composition comprises micronized fenofibrate, a surfactant and a binder cellulose derivative, which is used as a solubility enhancer, preferably hydroxypropylmethylcellulose. The cellulose derivative represents less than 20% by weight. of the composition. The bioavailability of the active ingredient is enhanced by the combination of micronized fenofibrate, a cellulosic derivative and a surfactant. The invention also relates to a process for the preparation of this composition without the use of an organic solvent. |