http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BG-65117-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d35bd938e5de8b37ed0c135746336358 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485 |
| filingDate | 2000-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdef713f22582aededc023dd0d5cffab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad660a6ed77e39b8e7cf89fc0c7f54ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac7bd8eaeb96410d03875629b9ff5156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7a3bbbe19269719546aa8c1d815aa4a |
| publicationDate | 2007-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BG-65117-B1 |
| titleOfInvention | SPEROIDES, COMPOSITION AND METHOD FOR OBTAINING THEM |
| abstract | The invention relates to a new pharmaceutical form in the form of spheroids, to a method for the preparation of such spheroids, and to multi-compound pharmaceutical preparations containing them. Spheroids include one or more major constituents, in addition to tiagabine, which can be compressed directly without the addition of a substantial proportion of excipients and are less than 5% by weight, preferably less than 1% by weight. Spheroids consist of a nucleus and / or a coating layer with at least one thermoplastic inert ingredient having a paste-like to semi-solid consistency, at a temperature of 20 degrees C and a melting point between 25 and 100 degrees C. It is coated with an elastic and deformable film of more than 50% elongation, determined by a known method, based on a polymeric material, in particular a film whose transition temperature is less than 30 degrees C, and provides either the preservation or masking of the taste of the active major ingredient, or modification and control of a comp Yanet. The polymeric material is a polymer or a mixture of at least one polymer and a plasticizer selected from the group consisting of triethyl citrate, acetyl triethyl citrate, tributyl citrate, acetyl tributyl citrate, triacetin, diethyl phthalate, polyethylene glycols, polysorbates, mono- and diacetylated glycerides itehni mixtures. The method for producing spheroids is arranged such that a layer containing at least one thermoplastic inert ingredient, the film of polymer material and the outer coating is successively deposited on the nuclei by means of |
| priorityDate | 1997-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.