abstract |
The invention relates to benzofuran derivatives of the general formula in which the meaning of A is selected from where Z is O or S; s is 0 or 1; q is 0 or 1; R 4 is hydrogen, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 1-6 alkylaryl or C 1-6 alkyl-O-aryl; D is a linking group selected from C1-6 alkylene, C2-6 alkenylene and C2-6 alkynylene, all with unbranched or branched chains; as well as their enantiomers and pharmaceutically acceptable acid addition salts. The compounds bind with high affinity to the 5-HT1A receptors. |