| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b94d2715cda37c1f23e48f9f4f23422
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2722fd2ecc8e1e55fbc3bb2ba9fc53fc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39541
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2875
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70521
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-343
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-443 |
| filingDate |
1999-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_290605e0ccac353946c943ec5fbb7209
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a5c991b5b41c8305615b0458f8876b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ad80ed666cc3a9b531d70361c171e61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08f108e5a624d3109fb538192c078752
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90ddb6e8b5834713ae16c3817d743647 |
| publicationDate |
2006-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BG-64841-B1 |
| titleOfInvention |
USE OF ANTI-CD40L (ANTI-CD154) ANTIBODY AT ANTIBODY FOR PROTECTING ADVERSE AGENTS IMMUNE ANSWERS, IN PARTICULAR IN REMOVAL OF A TRANSPLANTANT |
| abstract |
The compositions and methods are used to prolong the survival of the grafted tissue in a host recipient in order to avoid acute transplant rejection and to alleviate the immunological consequences of the graft failure. Tissue transplant rejection can be inhibited using an anti-CD40L (anti-CD154) antibody or antibody derivative, either alone or in combination with another immunomodulator or immunosuppressor. A synergistic combination includes an anti-CD40L (anti-CD154) antibody or antibody derivative and a CD28 signal delivery switch. An example of an anti-CD40L (anti-CD154) antibody or a derivative of an anti-CD154 monoclonal antibody is an antibody having the antigen-specific binding characteristics of the 5ss monoclonal antibody. An example of a CD28 signaling switch is a CTLA4-Ig fusion protein. |
| priorityDate |
1997-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |