| abstract |
The compounds exhibit leukotriene antagonistic activity and are used as valuable anti-inflammatory and antiallergic drugs and in the treatment of cardiovascular diseases. The novel benzopyran derivatives have the general formula wherein A is an oxygen or sulfur atom or a methylene group B and C are: 1) when B is a benzofused heterocycle wherein U is O, S or N atom, ZY are two carbon atoms , can be -CONR7-, CSNR7-, -SO2NR7-, -CH2O-, -CH = CH- group, 2) when B is a phenyl group. C may be -SO2NR7-, -CH2O-, -CH = CH- group, D is 5-tetrazolyl or -COOR8 group in which R8 is hydrogen, (C1-C4) -alkyl or phenylalkyl, and m and n are integers with a value between 0 and 4. |