abstract |
The invention relates to inhibitors of matrix metalloproteases, to pharmaceutical compositions containing them and to a method of their use for the treatment of a number of physiological conditions. They have the general formula wherein T is a pharmaceutically acceptable substituent; A is CH 2, CH or N; G is CH2 or CH; R1 may be one of the mentioned substituents. Said compounds contain a ring, fragments A and G of the formula are linked, the compounds are mixtures of diastereomers or individual diastereomers that form these mixtures. |