| abstract |
The invention relates to compounds having the general formulawhere the residues have the following meaning: R1 hydrogen,halogen; R2 hydrogen, halogen, NH2, phenyl-CH2CONH,phenyl-OCH2CONH, phthalmido, o-MeNHCIC6H4CONH,isoxazolylcarbonylamino; R3 is hydrogen, Me2C=C-COOMe,H2C=C(Me)-CH-COOMe, Me2C=C-COOCH2phenyl,H2C=C(Me)-CH-COOCH2C6H4NO2-p, Me2C=C-COOCH2C6H4NO2-p,Me2C=C-COOCH2C6H4Me-m, H2C=C(Me)-CHCOOCH2C6H4Me-m, Me2C=C-COOH;R4 hydrogen or sodium and R5 hydrogen, alkyl, benzyl or someheterocyle, e.g. isoxazole, pyrazole and others, and to theirsalts. The invention also relates to a method for their preprationand application as intermediate compounds in the synthesis of-lactam analogues or as active materials for the production ofpreparation for antibacterial therapy. |