http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BG-61418-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335 |
| filingDate | 1992-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c40ecda85d766366ecb54bd681ad844 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca0c34add22ceb2dc608c06e6b635cdc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afabce1a39936693edc4e4f965b7dc13 |
| publicationDate | 1997-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BG-61418-B2 |
| titleOfInvention | ANTIHIPERCHOLESTERINEMIC COMPOUNDS |
| abstract | A compound of the formula wherein R 1 is H or CH 3, R is 1,1-dimethylpropyl, C 3-10 cycloalkyl, C 2 -C 10 alkenyl, C 1 -C 10 alkyl substituted with CF 3, phenyl, halophenyl, phenyl- substituted phenyl-C1-3 alkyl in which the substituent is halo, C1-3 alkylyl, C1-3 alkoxy, the dotted lines at X, Y and Z denote possible double bonds which, if present, are either a combination of X and Z or X , Y or Z are independently or the corresponding dihydroxy acid of the formula or a pharmaceutically acceptable salt thereof, a C1-4 alkyl ester or a C1-4 alkyl ester of the acid, amesten with phenyl, dimethylamino or atsetilamino.6. A pharmaceutical antihypercholesterolemic composition comprising a pharmaceutical carrier and an antihypercholesteine-effective amount of a compound of structural formula I or a corresponding dihydroxy acid of formula II, or a pharmaceutically acceptable salt thereof, a C1-4 alkyl ester thereof or a C1- 4-alkyl ester of the acid substituted with phenyl, dimethylamino or acetylamino. A method of treating hypercholesterolemia patients which comprises administering an antihypercholesteinemically effective amount of a compound of structural formula I or a corresponding dihydroxy acid of formula II. |
| priorityDate | 1980-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.