http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BG-61265-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_634715a790f7ef0163a61e9f364bebcd |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate | 1992-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c14cd30ca643f220320934022ce81b3 |
| publicationDate | 1997-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BG-61265-B1 |
| titleOfInvention | Improved method for synthesis |
| abstract | The present invention relates to an improved method for thesynthesis of omeprazole, comprising the steps of reacting5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-1H-benzimidazole with m-chloroperoxy-benzoic acid in a methylenechloride solution at a substantially constant pH of about 8.0 to8.6; extracting the reaction mixture with aqueous NaOH; separatingthe aqueous phase from the organic phase; and adding an alkylformate to the aqueous phase, resulting in crystallization ofomeprazole. |
| priorityDate | 1990-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.