| abstract |
The invention relates to novel 19-norsteroid or 19-nor-homo-steroids substituted at position 11 of the general formula wherein r1 represents a hydrogen radical containing from 1 to 18 carbon atoms containing at least one nitrogen, phosphorus or silicon atom, the atom directly adjacent to the carbon at position 11 is a carbon atom, r2 represents a hydrocarbon radical containing from 1 to 8 carbon atoms, x represents a residue of a pentagonal or hexagonal ring, optionally substituted or unsubstituted, the group c = a in position 3 representing and an oxo group, free or blocked in the form of a ketal, a group of the group c = n, a group of c = no-alc3 or a group cn2, alc1, alc2 and alc3 represent an alkyl radical containing from 1 to 8 carbon atoms or an alkyl group comprising 7 up to 15 carbon atoms, and in and form together a double bond or an epoxy bridge. The invention also relates to salts of said compounds obtained by reaction with acids, to a process for their preparation, to their use as medicaments and to compositions containing them. |