http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BG-51808-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d85b1274250a3737ec15f632fbd5260 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 |
filingDate | 1991-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2484471b741f581ea772e4b51c344263 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8fdc8a74cbdcaca33c5fe2a795f379b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85edb56d132979a7cd4db6545cdccc95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebc2eac9270b332b1f96351e5152a1f6 |
publicationDate | 1993-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | BG-51808-A1 |
titleOfInvention | Process for preparation of sodium salt of penicillanic acid-1,1-dioxide |
abstract | This method finds application in the pharmaceutical industry. It is performed on a technological scale and ensures high yields and quality of the final product with no requirement to operate in non-aqueous organic environments and no use of hygroscopic reagents. The compound obtained thereby can be used as an inhibitor of β-lactamases in combination with β-lactamic antibiotics resulting in broadening the spectrum and increasing the activity of these antibiotics. The method involves dissolving 1 parts by weight of penicillanic acid-1,1-dioxide in 10-15 parts by weight of water-micible organic solvent. An equivalent amount of saturated aqueous solution of sodium carbonate is added to the filtrate after filtration, the mixture is homogenized for 60-90 minutes and the released product is filtered, washed with the same solvent and dried. |
priorityDate | 1991-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 17.