http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BG-112905-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f058a71899e153cedc18883bad5b31a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D11-0492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07G5-00 |
| filingDate | 2019-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7c527a76a28215a287bc2179580e57d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c3e424b32832bfde4963aa1345931f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21b11c61f8287a80c36ab84e41f03b9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d490e933abccd177e3912309b906d252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d6992589b12c69318a7903e626bbbf6 |
| publicationDate | 2019-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BG-112905-A |
| titleOfInvention | METHOD FOR Isolation of cytisine |
| abstract | The invention relates to a method for isolating cytisine from plant material. The process according to the invention consists in extracting the vegetable raw material with a lower alcohol acidified with a mineral acid to a pH in the range of 1.5-3.5. The combined alcohol-aqueous extracts were concentrated in vacuo to remove the alcohol and, after filtration, extracted with chloroform, methylene chloride, butyl acetate or normal butanol in a 1: 1 ratio. The ballast-treated acidic aqueous concentrate is basified to pH 9-12 alkaline hydroxide or ammonium hydroxide and the alkaline aqueous concentrate is extracted at least twice with chloroform, methylene chloride, butyl acetate or normal butanol in a ratio of concentrate: 1 to 1 extractant 10. The combined organic extracts were evaporated to dryness, then acetone or ethyl acetate was added to give a suspension which was allowed to crystallize completely at 5-10 C, then filtered and dried. The insulated product has a high yield and purity. |
| priorityDate | 2018-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.