http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BG-109179-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate | 2005-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2979e9927675abfe8aabb72268c174e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e878e9b04561f194ef1e446d1720ec9f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a1b658e547f1a645124312561081cf3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_197118308f6077fa5842cc84f13aaf08 |
| publicationDate | 2006-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BG-109179-A |
| titleOfInvention | XINOLINE DERIVATIVES AS ANTIBACTERIAL FACILITIES |
| abstract | The invention relates to the use of a compound for the manufacture of a medicament for the treatment of bacterial infections, a pharmaceutically acceptable acid or base addition salt of said compound, a stereochemically isomeric form thereof or an N-oxide form thereof. The compound has the formula wherein R1 is hydrogen, halogen, polyhalo-C1-6alkyl, C1-6alkyl, Ar or Het; p is 1 or 2; R2 is C1-6 alkyloxy, C1-6 alkyloxyC1-6 alkyloxy or C1-6 alkylthio; R 3 is Ar, Het or Het 1; R 4 and R 5 are each independently hydrogen, C 1-6 alkyl or benzyl; or R4 and R5 taken together and including the N to which they are attached may form a radical selected from the group of pyrrolidinyl, 2-pyrrolinyl, 3-pyrrolinyl, pyrrolyl, imidazolidinyl, pyrazolindinyl, 2-imidazolinyl, 2pyrazolinyl, imidazolyl, pyrazolyl, triazolyl, piperidinyl, pyridinyl, piperazinyl, pyridazinyl, pyrimidinyl, pyrazinyl, triazinyl, morpholinyl and thiomorpholinyl, each of said rings being optionally substituted with C 1-6 alkyl, halogen, polyhaloC 1-6 alkyl, hydroxy, C 1-6 alkyl, C 1-6 alkyloxy, amino, mono-rings (C 1-6 alkyl) amino, C 1-6 C 1-6 alkyloxyC 1-6 alkyl, C 1-6 alkylthioC 1-6 alkyl or pyrimidinyl; R6 is hydrogen, halogen, polyhaloC1-6 alkyl, C1-6 alkyl, C1-6 alkyloxy, C1-6 alkylthio; or two adjacent radicals R6 taken together form a bivalent radical of formula -CH = CH-CH = CH-; r has the value 1 or 2; R7 is hydrogen, C1-6 alkyl, Ar, Het or Het1. The invention also relates to the |
| priorityDate | 2005-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 259.