| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d4f0e254c73f422758c61fb7bb0f991 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 |
| filingDate |
2004-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f0a3032c400889e05ff25cb8ad8cfe0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_505b3a8aae9350844a2f5a3e3707bbc4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f38254f7bc991de70c1a32852946e87b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e52ce547be1997eab5fa4767acc0d6e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f0d1c1f8707286caa6b27e9b5b39f0a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eab28ab26a77bdd6179adc9dac0ff9dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5e570258d8bfe3b05c88442ca09b4fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2450f30e0e88f82b4b8295f50414a036
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88abdb227217a1538ed8624793ec2301 |
| publicationDate |
2005-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
BG-108549-A |
| titleOfInvention |
METHODS DEFINING DIABETES FOR D-ALA-D-ALA LIQUID INHIBITORS AS ANTIBACTERIAL MEDICINES |
| abstract |
According to the invention, some small molecules can bind to the ATP binding site of D-Ala-D-Ala ligase, even in the absence of an enzyme substrate, and can cause structural changes in the enzyme structure similar to those obtained upon binding of the D-Ala-D-Ala ligase. ATP and enzyme substrate. Such a structural change is required to activate or inhibit the enzyme. An advantage of the invention is the ability to identify key interactions in the active sites of the enzyme and to design and optimize inhibitors. a |
| priorityDate |
2001-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |