abstract |
CETP inhibitors have improved solubility and bioavailability in a lipophilic carrier containing a nutrient oil, a lipophilic solvent or a surfactant. Preferred compositions are self-emulsifying and self-micro-emulsifying, which include a CETP inhibitor, a co-solvent, a surfactant with an HLB of from 1 to 8, a surfactant with an HLB of more than 8 to 20, and optionally a nutritional oil. a |