| abstract |
A compound of formula wherein B is a phenyl ring, a 5 to 10 membered heteroaromatic group containing one or more heteroatoms, or naphthalenyl, 5, 6, 7, 8-tetrahydronaphthalenyl, benzo[1,3] dioxolyl or biphenyl group; A represents a group selected from -CH2-, -CH=CR9- -CR9=CH-, -CR9R10-,-CO-, -O-, -S-,-S(O)-, -S(O)2- and NR9, R9 represents a group of structure: R5 represents an alkyl group of 1 to 7 carbon atoms, an alkenyl group containing 2 to 7 carbon atoms, an alkyl group containing 2 to 7 carbon atoms, acyloalkyl group of 3 to 7 carbon atoms, a group of formula Wherein q = 1 or 2 and R11 is as defined above; R6 represents a hydrogen atom, a hydroxy group, a methyl group or a -CH2OH group; and X- represents a pharmaceutically acceptable anion of a mono- or polyvalent acid. The meaning of R1, R2, R3 are given in the description. 36 claims |