abstract |
The invention relates to a method for the production of 4-(17alpha substituted 3-oxoestra-4,9-dien-11beta-yl)benzaldehyde-(1E or 1Z)-oximes of general formula where R1 = H, C1-6 alkyl or a CnF2n+1 group; R2 = C1-4 alkyl, X = E or Z-OH; and Y = OC1-6 alkyl, SC1-6 alkyl or OCH2CnF2n+1, where n = 1, 2 or 3, which produces the target compounds with high yield and selectivity. 6 claims |