abstract |
The invention relates to compounds of the formula wherein R1, R2, R3, R4, R5, R6, p, q and n have the meanings and values indicated in the description and their pharmaceutically acceptable salts and in vivo hydrolysable esters. The invention also relates to methods for preparing the compounds and for their use as medicaments, in particular for producing cell cycle inhibitory activity (anti-cellular proliferation) in a warm-blooded animal, including man. |