http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BG-106522-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69c91bbf0395db010b4806f50d808c4e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-08 |
filingDate | 2002-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_177f2d8692d5fce8eb7c8b2913f673ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99b9f29fc1fde8164d1fd47ba08028b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aeb9eb017c35f2265bd12aec76aa63ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a9a3549c6c48a877ead74c62b4ffe8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa23c83a6b600eab2363cb67ee0c21be http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_406dee54bae7d4bd1cb33ff04e8c2304 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0430359163c605c3452a53ce8846979 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b3998868aeac6950afccd84db48ed29 |
publicationDate | 2003-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | BG-106522-A |
titleOfInvention | A METHOD FOR OBTAINING AN ALMAMINE DISSOLVED DERIVATIVES AND THEIR RELEVANT SALTS |
abstract | The invention relates to a process for the preparation of (E) -N-methyl-N- (1-naphthylmethyl) -6,6-dimethylhept-2-en-4ynyl-1-amine of the formula I, of its corresponding acid salts. By the process, the chloro compound of the formula IIIb described in the description containing the E and Z isomers in the ratio of 3.3-3.4: 1 and obtained by the reaction of the secondary alcohol of formula IV of the description with hydrochloric acid reacts with the secondary amine of formula II from the description in a solvent-type aliphatic ketone in the presence of a base and, if desired, a iodide salt catalyst. Then, the compound of formula I obtained in basic form and isomer ratio of 3.3-3.4: 1 is converted directly into the hydrochloric acid salt with hydrochloric acid, the precipitated hydrochloride of the E-isomer is removed, if desired, the base is liberated and is converted to a pharmaceutically acceptable acid salt by a known method. The resulting product is an active agent of a known antifungal drug. |
priorityDate | 2002-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.