http://rdf.ncbi.nlm.nih.gov/pubchem/patent/BG-106203-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bde28565d28f037e78bf4a67776ee24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01L21-00 |
| filingDate | 2001-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcdefeccbb19703e609c591b5f35f7d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c75f07838a8a23c74523afb6436a2ab3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fab9bd5f2956a73ab96a12ae41662b6c |
| publicationDate | 2002-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | BG-106203-A |
| titleOfInvention | METHOD FOR OBTAINING A CLEAN CITALOPRAM |
| abstract | The invention relates to a process for the preparation and purification of citalopram of the formula ## STR2 ## In the process of the present invention, Z is iodine, bromine, chlorine or CF3- (CF2) n-SO2-O- and n is 0 to 8, is subjected to a cyanide exchange reaction with a cyanide source. The resulting crude citalopram is subjected to an initial purification and subsequent treatment with an amide or amide-forming agent. The reaction mixture is subjected to acid / alkaline washing and / or crystallization and recrystallization of citalopram to remove the formed amides from the crude citalopram mixture. The resulting citalopram product is optionally further purified, treated and / or isolated as the base or as a pharmaceutically acceptable salt thereof. |
| priorityDate | 2000-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.